Cerebrospinal fluid (CSF) circulates through the central nervous system, providing mechanical protection, nutrient delivery and metabolic waste clearance. In recent years, the concept of a glymphatic ...

The glymphatic system was first explained 1 as a macroscopic waste clearance system that utilizes astroglial (glial-lymphatic) channels to eliminate soluble proteins and metabolites from the central ...

Biomedical engineers at Duke University have developed a technique to noninvasively visualize the brain's waste-removal ...

A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box ...

Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain's natural waste drainage system—a discovery that could open new avenues for tackling ...

Research headed by teams at the University of Rochester Center for Translational Medicine and the University of Copenhagen describes for the first time how a spreading wave of disruption and the flow ...

Fighting Alzheimer’s disease is a race against time. By the time most patients are diagnosed and treated, their cognitive symptoms have already advanced significantly. New research, though, pinpoints ...

A study linked spontaneous spinal CSF leaks to genetic variants that weaken connective tissue around the spinal cord, ...

Brain-derived extracellular vesicle (EV) biomarkers represent a promising frontier for liquid biopsy development targeting the nervous system. They offer strong potential for enabling minimally ...

Whole-exome sequencing revealed variants in a gene that compromise connective tissue integrity and may increase a person’s ...