The kinetics of amyloid beta turnover within human brain is still poorly understood. We previously found a dramatic decline in the turnover of Aβ peptides in normal aging. It was not known if brain ...

A multitude of genes have been linked to the development of Alzheimer's disease. Specifically how those genes might influence the progression of neurodegeneration remains something of a black box ...

Biomedical engineers at Duke University have developed a technique to noninvasively visualize the brain's waste-removal ...

Fighting Alzheimer’s disease is a race against time. By the time most patients are diagnosed and treated, their cognitive symptoms have already advanced significantly. New research, though, pinpoints ...

Cerebrospinal fluid (CSF) circulates through the central nervous system, providing mechanical protection, nutrient delivery and metabolic waste clearance. In recent years, the concept of a glymphatic ...

Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain's natural waste drainage system—a discovery that could open new avenues for tackling ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Cognito Therapeutics, a neurotechnology company advancing disease-modifying therapies to treat CNS diseases, today announced the publication of a study in ...

Researchers at Cedars-Sinai Health Sciences University and Johns Hopkins University have identified genetic mutations that may explain why some people develop a spontaneous cerebrospinal fluid (CSF) ...

Whole-exome sequencing revealed variants in a gene that compromise connective tissue integrity and may increase a person’s ...

Brain-derived extracellular vesicle (EV) biomarkers represent a promising frontier for liquid biopsy development targeting the nervous system. They offer strong potential for enabling minimally ...

A study linked spontaneous spinal CSF leaks to genetic variants that weaken connective tissue around the spinal cord, ...