If you took biochemistry classes, chances are good you remember memorizing the Krebs cycle, a well-known metabolic pathway in which sugars are converted through a series of steps to generate ATP, a ...

As longtime fans of both Macklemore and metabolism pathways (weird combo, we know, but whatever), we’re pretty damn excited about this “Thrift Shop” parody by Wilson Lam. You should be, too, ...

The Krebs cycle represents a common meeting place of carbohydrate, lipid, and protein metabolism. It variously serves as a means to produce energy, generate intermediates, and convert molecules from ...

A new study identifies recessive, loss-of-function mutations in IDH3B, encoding a subunit of the NAD-specific isocitrate dehydrogenase, in individuals with retinitis pigmentosa. The lack of any ...

Like most medical students, I struggled to memorize the Krebs cycle, the complex energy-producing process that takes place in the body's mitochondria. Rote learning of Sir Hans Krebs' eponymous ...

Two simple molecules can react to form most of the intermediates in an analog of the modern-day Krebs cycle, without the need for enzymes or metals, according to a new study (Nat. Chem. 2020, DOI: ...

Metabolism is a key process in living things that enables fuel to be turned into energy, but its evolutionary origin is a long-standing enigma. Now, a study by US researchers has found a simple ...

A set of biochemical processes crucial to cellular life on Earth could have originated in chemical reactions taking place on the early Earth four billion years ago, believes a group of scientists. A ...

Reverse electron transport (RET) driven by the oxidation of succinate has been proposed as the mechanism of accelerated production of reactive oxygen species (ROS) in post-ischemic mitochondria.