Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

In a landmark achievement in biological imaging, researchers at Biohub and the University of California, Berkeley today ...

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...

In a landmark achievement in biological imaging, researchers at the University of California, Berkeley and Biohub today ...

Installed in a custom Titan Krios, the laser phase plate enhances motion correction, early‑frame recovery, and 3D classification and alignment.

A new kind of microscope is giving scientists a way to watch life inside cells with a clarity that feels almost unfair. Instead of choosing between seeing big structures or tiny particles, researchers ...

A project at the University of Tokyo has developed a bidirectional scattering microscopy technique for imaging complex cell structures. Discussed in Nature Communications, the platform is designed to ...

(A) When a traditional Gaussian beam is used, diffraction causes the illumination beam to widen at the edges. (B) Joint optimization scheme. A network predicts the positions of beads in the focal ...