PIEZO1, a mechanosensor in endothelial cells, plays a critical role in fetal vascular development during embryogenesis. However, its expression and function in placental trophoblasts remain unexplored ...

Preeclampsia, intrauterine fetal growth restriction, and other "great obstetrical syndromes" have been linked to disordered placenta development, so understanding the structure and function of this ...

Both epidemiological and animal studies suggest that adverse environment during pregnancy can change the offspring development programming, but it is difficult to achieve prenatal early warning. In ...

Researchers have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for ...

Most people talk about diet and lifestyle of the mother when it comes to pregnancy and a baby's health. But new studies are indicating that paternal nutrition and health during the very beginning of ...

The placenta is a pancake-shaped organ that develops within the wall of your uterus and connects to your baby though the umbilical cord. By the end of pregnancy, it grows to be about 9 inches in ...

Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol—a necessary hormone for fetal development—and this would affect the baby's development from very early ...