Adenomatous polyposis coli (APC) is a tumor suppressor whose loss is intimately linked with colon cancer. APC is an essential component of the Wnt signaling pathway and is required for the formation ...

Cilia are microtubule-based organelles that protrude out of the cell surface, mainly composed of cilia membrane and axial filament. Cilia are very conservative during evolution process, found in many ...

Researchers have developed an innovative drug treatment for familial adenomatous polyposis (FAP), a rare, inherited condition that affects adolescents and young adults and often leads to colorectal ...

In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system ...

Comprehensive genomic profiling of ctDNA in patients with colon cancer and its fidelity to the genomics of the tumor biopsy.

Juvenile polyposis syndrome is a genetic condition characterized by the formation of polyps in the colon, or more rarely, in the stomach of the affected young person. Most cases present by the time ...

Gardner syndrome is a genetic disorder characterized by multiple intestinal polyps, dental abnormalities, multiple osteomas, and mesenchymal tumors of the bone and soft tissues. Gardner syndrome is a ...