Protein microarrays are emerging as one of the most active areas in biotechnology today. Steady advances are overcoming initial skepticism as to their feasibility and utility. Industry sources project ...

High-Throughput and Multiplexed Assays Augment Biomarker Discovery and Diagnostics High-throughput proteomics using microarray-based technology and proteome chips is accelerating protein-biomarker ...

Researchers in the laboratory of R. Graham Cooks at Purdue University have developed a mass spectrometry-based method of creating protein arrays. The technique, known as ion soft-landing, selects ...

Protein arrays are a relatively new technique for studying protein-protein interactions and profiling antibody binding and specificity, and in the past year a number of companies have released premade ...

Cell or tissue lysates are arrayed on nitrocellulose-coated slides (Grace Bio-labs, Bend, OR) in triplicate using the Aushon 2470 Arrayer (Aushon BioSystems, Billerica, MA) (technical replicates).

Scientists at Northwestern University have developed a new detection technology on the nanometer scale that could lead to the next generation of proteomic arrays and new methods for diagnosing ...

A research team has discovered an astounding array of unexplored protein folds. This research will expand our understanding of the depth of the protein universe and the possibilities for de novo ...

The von Hippel–Lindau tumor suppressor gene product (pVHL) is an E3 ligase substrate receptor that binds proline-hydroxylated hypoxia-inducible factor HIF1α, leading to its ubiquitin-dependent ...

Molecularly characterized patient tumors and cancer cell lines lay a critical foundation for modern cancer research, enabling the study of intertumor heterogeneity and oncogenic mechanisms, as well as ...

A new study has shed new light on the astonishing diversity of protein structures and their folds in nature. Researchers set out to reveal the extent to which nature has explored the vast landscape of ...