Scientists report that they have learned how certain combinations of rearranged genes can promote the progression of a rare type of kidney cancer. In findings from a study led by investigators at the ...

Despite a host of checks and balances that usually prevent harmful genetic mutations, sometimes mistakes happen, with serious ...

Infant leukemia linked to rearrangements of the NUTM1 gene has shown remarkably strong outcomes on current therapy in ...

Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

Cancer is caused by faulty genes, but what also shapes a cancer cell's behavior is how a gene's instructions are trimmed and ...

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study. The findings offer a new ...

A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome. Unstable genomes are a fertile playground for cancer ...

Extrachromosomal DNAs (ecDNAs) are circular DNA structures located in the nuclei of cells outside chromosomes. They were originally discovered in chromosome spreads of cells obtained from embryonal ...

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. DNA doesn’t just carry information in its sequence; fleeting alternative folds like i‑DNA ...

Normal TFE3 protein appears diffuse throughout a cell (left), whereas the TFE3 fusion proteins found in a rare kidney cancer form tiny liquid droplets near the cell’s DNA, where they regulate ...