The Green Wave are 5.5-point favorites in the latest Tulane vs. UTSA odds, while the over/under for total points scored is 54.5 via SportsLine consensus. Before making any UTSA vs. Tulane picks, check out the college football predictions from the SportsLine Projection Model .

The Tulane Green Wave (6-1) hit the road for an AAC battle against the UTSA Roadrunners (3-4) on Thursday, October 30, 2025 at the Alamodome. The Green Wave faced the Army Black Knights in their most recent game, winning 24-17. Their last time out, the Roadrunners were beaten by the North Texas Mean Green 55-17.

Tulane head coach Jon Sumrall has been heavily linked to LSU this week. He was upset by a previously 3-4 team on Thursday night.

The University of Texas at San Antonio is planning to host the Lone Star State’s newest Division I football program to kick off its 2026 season.

The Roadrunners are 21-0 in home conference games under Traylor and will tap into that magic once again. Spurred by the sting of a blowout loss at North Texas, UTSA will deliver an upset mirroring last season's win against Memphis, potentially sparking a late-season surge.

UTSA head football coach Jeff Traylor had to set the record straight in his postgame press conference on Thursday night: the Roadrunners are not cheaters.  It hasn't been the best season for UTSA, which is 4-4 so far and ranked eighth in the American Conference,

What the analytics predict for Tulane vs. UTSA in this Week 10 college football game from an expert model that simulates games and projects scores.

Still undefeated in American Conference play, Tulane hits the road for the first time in a month for what could be a shootout at the Alamodome.

The Roadrunners will have plenty of competition for eyes and attendance during Thursday night's meeting with the Green Wave in the Alamodome.

In a nationally televised game on Thursday night, Tulane got walloped by Texas-San Antonio, 48-26. With the loss, the Green Wave falls to 6-2 on the year, 3-1

This article was originally published on greengoldandbold.com as ESPN will shine a spotlight on USF with SportsCenter on campus before the UTSA game.