Figure 1: Expression of BRCA1 restores the G2/M checkpoint and regulates the expression and activity of checkpoint proteins. Arrest at the G2/M boundary after DNA damage prevents progression of the ...

“Love, Danielle” is not a documentary, but it incorporates real surgical footage from its co-writer and star, Devin Sidell, ...

Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer's disease. BRCA1 is a key protein ...

FZOCUS-1 assessed the safety and efficacy of fuzuloparib alone and in combination with apatinib for patients with newly diagnosed or advanced ovarian cancer.

The full name of the BRCA1 gene is “breast cancer 1, early onset,” and it codes for a tumor suppressor protein. Tumor suppressor proteins help repair DNA that has become damaged in order to ensure the ...

Researchers with the Harold C. Simmons Comprehensive Cancer Center recently discovered the BRCA1 gene is necessary for the survival of blood-forming stem cells. This could explain why patients with ...

Thoracic Radiotherapy Improves the Survival in Patients With EGFR-Mutated Oligo-Organ Metastatic Non–Small Cell Lung Cancer Treated With Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors: A ...

Germline pathogenic variants (gPVs) occur in a subset of patients with ovarian cancer, with the highest prevalence among those with Ashkenazi Jewish ancestry, followed by Asian and Hispanic patients, ...

A new research has revealed that BRCA1, the breast cancer susceptibility gene, plays an important role in non-small cell lung cancer (NSCLC). Hence, it can also be used to predict outcome for patients ...