eLife

REM sleep prefrontal high-frequency oscillation chains mediate distinct cortical – hippocampal reactivation patterns compared to NREM sleep

REM (rapid eye movement) and non-REM (NREM) sleep stages contribute to systems memory consolidation in hippocampal-cortical circuits. However, the physiological mechanisms underlying REM memory ...
eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
IEEE

Optimizing High-Level Synthesis Sparse Matrix-Vector Kernel for Alveo FPGAs

Abstract: Sparse matrix-vector multiplication (SpMV) is a critical kernel in scientific computing and high-performance applications, yet it remains challenging to optimize due to irregular memory ...
IEEE

An Array-Based IC for the Characterization of Aging in Standard Cells

Abstract: As aging effects become more pronounced in scaled technologies, designing aging-tolerant circuits with minimal guardband overhead is increasingly critical. This requires accurate propagation ...
Frontiers

Osteopontin-expressing valvular interstitial cell subpopulation as a driver of extracellular matrix remodeling in aortic valve disease

Aortic valve disease (AVD) is a cardiovascular disorder highly prevalent in the elderly population. Aortic valve leaflets suffer hardening due to extracellular matrix (ECM) remodeling and subsequent ...