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  1. Estradiol Vaginal Cream: How to Use & Side Effects

    Estradiol vaginal cream is a medication that treats irritation, dryness and pain during sex caused by menopause. Menopause is a natural part of aging and marks the end of your reproductive …

  2. Estradiol (vaginal route) - Side effects & dosage - Mayo Clinic

    Dec 1, 2025 · These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or …

  3. By the way, doctor: Is vaginal estrogen safe? - Harvard Health

    Aug 17, 2021 · Estrogen loss can lead to thinning (atrophy) of the cells lining the vagina and urethra. As a result, women may develop vaginal dryness, itching, and pain with intercourse, …

  4. Estradiol vaginal Uses, Side Effects & Warnings - Drugs.com

    Feb 6, 2025 · This medication guide provides information about estradiol vaginal for systemic treatment of certain symptoms of menopause, including hot flashes and vaginal dryness, …

  5. Common and Rare Estradiol Vaginal Cream Side Effects You

    Sep 25, 2024 · Read on to learn the side effects of using estradiol vaginal cream, including both mild and more serious side effects, and how to manage them.

  6. Estradiol vaginal (Estrace, ­Estring, Vagifem) - Uses, Side Effects ...

    Oct 20, 2024 · Overview: Vaginal estradiol is available as a cream, insert, or ring that is inserted into the vagina to increase estrogen levels. It is used after menopause to reduce vaginal …

  7. Estrogen Vaginal: MedlinePlus Drug Information

    Estrogen Vaginal: learn about side effects, dosage, special precautions, and more on MedlinePlus

  8. Side Effects of Vaginal Estrogen and Non-Hormonal Options …

    Jul 11, 2025 · Even though vaginal estrogen is designed to help with dryness and discomfort, some people notice the opposite at first — a little more itching, stinging, or general irritation …

  9. Side effects of vaginal oestrogen - NHS

    Like all medicines, vaginal oestrogen may cause side effects, but it's common to have no side effects or only minor ones. These common side effects of vaginal oestrogen happen in more …

  10. Estradiol vaginal cream side effects guide — Optum Perks

    Estradiol vaginal cream is prescribed to help reduce vaginal symptoms of menopause. It’s an estrogen hormone drug that may cause mild or serious side effects, including cardiovascular …